Adventure Gamers has an interview up with Joel DeYoung of Hothead Games on the development of the Penny Arcade RPG, On The Rain-Slick Precipice of Darkness. Actually, the interview's been up for about a month, but that shouldn't stop you from wandering over and examining the madness.
Everything I hear about the creation of this game fills me with a sense of deep foreboding. It's not just the tacked on Mary-Sue protagonist - it's also that the game is set in a kind of steampunk 1920s, apparently features no gaming-related jokes, and will require you to regularly "level up". This is exactly the sort of thing that under any normal circumstances would receive an exceptionally high degree of mocking from the talented fellows at Penny Arcade.
Anyway, I had previously been betting on this torrid monstrosity turning into vaporware, and that's looking less and less likely, so there's always the chance that it could continue to defy expectations. At least they're paying attention to Telltale Games' success with Sam & Max, which is probably a good thing.
As a kind of bonus, the interviewer chats to Ron Gilbert about Deathspank. That game doesn't seem to have yet moved beyond the level of "extended practical joke", so I'll stay tuned for more on that topic once there's something to be said about it.